IRF7 Regulates TLR2-Mediated Activation of Splenic CD11chi Dendritic Cells
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چکیده
منابع مشابه
IRF7 Regulates TLR2-Mediated Activation of Splenic CD11chi Dendritic Cells
Members of the Interferon Regulatory Factor (IRF) family of transcription factors play an essential role in the development and function of the immune system. Here we investigated the role of IRF7 in the functional activation of conventional CD11c(hi) splenic dendritic cells (cDCs) in vitro and in vivo. Using mice deficient in IRF7, we found that this transcription factor was dispensable for th...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0041050